منابع مشابه
Endosomes make tracks
arly endosomes may help to create their own short-range tracks, according to a report from Stéphane Gasman, Yannis Kalaidzidis, and Marino Zerial (Max Planck Institute, Dresden, Germany). The results also suggest parallels between membrane trafficking, signaling, and regulation of the cytoskeleton. Trafficking of early endosomes requires the small GTPase RhoD. Zerial’s group identified the firs...
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L arge-scale polarity, an essential property of many cells, requires active mechanisms for both establishment and maintenance. In eukaryotic cells, parallel-oriented arrays of actin filaments and or microtubules frequently provide a structural framework for polarity. For example, actin cables mediate polar growth in yeast cell division, microtubules in neuronal axons determine the directionalit...
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Theories of shapes are important for object recognition and for reasoning about the behaviour of objects, both tasks strongly constrained by shape. Whereas the extraction of shape properties has extensively been studied in vision, there is still a lack of qualitative shape descriptions which allow reasoning about shapes with AI techniques in a flexible manner. In this paper we present a qualita...
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After endocytosis, lysosomally targeted ligands pass through a series of endosomal compartments. The endocytic apparatus that accomplishes this passage may be considered to take one of two forms: (a) a system in which lysosomally targeted ligands pass through preexisting, long-lived early sorting endosomes and are then selectively transported to long-lived late endosomes in carrier vesicles, or...
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Heparin sustains the brain myloid plaque formation can be inhibited by an unlikely culprit, according to work by Scholefield et al. on page 97. The group finds that heparan sulfate (HS)—normally a part of the cell surface and extracellular matrix—functions in cells to slow the production of the plaque components of Alzheimer's disease. Amyloid plaques are aggregates of the amyloid -peptide (A ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1606rr4